Stereospecific Synthesis and Biological Evaluation of Farnesyl Diphosphate Isomers. -The diphosphates (Ia) and (II) are found to be very potent substrates for mammalian protein-farnesyl transferase. The isomer (Ib) is a submicromolar inhibitor of the transferase. -(SHAO, YING; EUMMER,
β¦ LIBER β¦
ChemInform Abstract: Grignard-Mediated Synthesis and Preliminary Biological Evaluation of Novel 3-Substituted Farnesyl Diphosphate Analogues.
β Scribed by Todd J. Zahn; Carolyn Weinbaum; Richard A. Gibbs
- Publisher
- John Wiley and Sons
- Year
- 2000
- Weight
- 30 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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