A new approach towards the synthesis of glycosides based upon a (formal) insertion of glycosylidene carbenes into 0-H bonds is presented. The synthesis and characterization of the glycosylidene-derived diazirines 25-28, precursors of glycosylidene carbenes, are described. The diazirines were prepare
ChemInform Abstract: Glycosylidene Carbenes. Part 25. Glycosidation of Ginkgolides B and A.
โ Scribed by M. WEBER; A. VASELLA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Carbenes. Part 25. Glycosidation of Ginkgolides B and A. -The title reaction with diazirine-derived glycosylidene carbenes can be conducted under either photolytic or thermal conditions. Depending on the amount of the diazirine ginkgolide B leads to either mono-, di-, or triglucosides. The use of THF as solvent gives mostly ฮฒ-D-glucosides. -
๐ SIMILAR VOLUMES
Glycosylidene Carbenes. Part 26. The Intramolecular FโขโขโขHO Hydrogen Bond of 1,3-Diaxial 3-Fluorocyclohexanols. -The ab-initio calculations of 3-fluorocyclohexanol and related systems concerning the FโขโขโขHO bonds are reported. The highly soluble rigid fluoro diols (D-I) and (L-I) are prepared and thei