ChemInform Abstract: General Asymmetric Synthesis of Hydroxymethylene and Hydroxyethylene Peptide Isosteres.
β Scribed by Y. AOYAGI; R. M. WILLIAMS
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Synthesis of a New C 2 -Symmetric Molecule with Dimeric Hydroxyethylene Isosteric Moiety. -The synthesis of a new type of C 2 -symmetric molecule (VIII) having a dimeric hydroxyethylene isosteric moiety by Cu(II) mediated dimerization of the amino acid derived sodium enolate of (III) as key step is