ChemInform Abstract: Synthesis of a New C2-Symmetric Molecule with Dimeric Hydroxyethylene Isosteric Moiety.

✍ Scribed by T. K. CHAKRABORTY; S. DUTTA

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 38 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199808173

✦ Synopsis

Synthesis of a New C 2 -Symmetric Molecule with Dimeric Hydroxyethylene Isosteric Moiety.

-The synthesis of a new type of C 2 -symmetric molecule (VIII) having a dimeric hydroxyethylene isosteric moiety by Cu(II) mediated dimerization of the amino acid derived sodium enolate of (III) as key step is described. The title compound has a potential application in the development of new HIV-protease inhibitors. -(CHAKRABORTY, T.