Condensation reactions of o-phenylenediamine and two equivalents of acetophenone under gallium(III) triflate catalysis produce biaryl-substituted 1,5-benzodiazepines. Similar reactions of o-phenylenediamine or o-aminothiophenol and o-hydroxy chalcones lead to formation of functionalized 1,5-benzodia
✦ LIBER ✦
ChemInform Abstract: Ga(OTf)3-Promoted Condensation Reactions for 1,5-Benzodiazepines and 1,5-Benzothiazepines.
✍ Scribed by Xiang-Qiang Pan; Jian-Ping Zou; Zhi-Hao Huang; Wei Zhang
- Book ID
- 102028931
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 34 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Novel polysubstituted ‐1,5‐benzothiazepine, ‐1,5‐benzoxazepine, and ‐1,5‐benzodiazepine were prepared in good yields by the reaction of hydrazono derivatives with __o__‐thioaminophenol, __o__‐aminophenol and __o__‐phenylenediamine __via__ a one‐pot reaction.