ChemInform Abstract: Fusidienol A: A Novel Ras Farnesyl-Protein Transferase Inhibitor from Phoma sp.
โ Scribed by S. B. SINGH; R. G. BALL; D. L. ZINK; R. L. MONAGHAN; J. D. POLISHOOK; M. SANCHEZ; F. PELAEZ; K. C. SILVERMAN; R. B. LINGHAM
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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Stereospecific Synthesis of a Novel Farnesyl Protein Transferase Inhibitor, Valinoctin A and Its Analogues. -The valinoctin A analogue (VIII), prepared via Curtius rearrangement of an intermediate azide, shows essentially the same inhibitory activity as the parent compound. -