ChemInform Abstract: Functionalization of a β-Lactam Ring via Nucleophilic Displacement of a 4-Vinyloxy Substituent.

✍ Scribed by Zbigniew Kaluza

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199920032

✦ Synopsis

Functionalization of a β-Lactam Ring via Nucleophilic Displacement of a 4-Vinyloxy Substituent.

-Similar to an acyloxy group the 4vinyloxy substituent in β-lactams (I) and (III) can be displaced by nucleophiles in the presence of a Lewis acid.