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ChemInform Abstract: Functionalization of 1-Methyl-1H-imidazole-5-carboxylic Acid at the C-2 Position: Efficient Syntheses of 2-Substituted t-Butyl 1-Methyl-1H-imidazole-5-carboxylates.

✍ Scribed by James P. Collman; Min Zhong; Roman Boulatov


Publisher
John Wiley and Sons
Year
2000
Weight
31 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Preparation and Structure Determination of 1-Benzyl-, 1-Methyland 1H-5-((2-Nitro-2-phenyl)ethenyl)imidazoles. -The title compounds (VIII) are synthesized by the Knoevenagel reaction of aldehyde (VI) with phenylnitromethane (VII). Only traces of (Z)-isomers of (VIII) are found in the reaction mixtur