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ChemInform Abstract: Friedel—Crafts Heteroarylation of (Hetero)arenes: A Facile Entry to 4-(Hetero)aryl Quinazolines and Quinolines.

✍ Scribed by Shailesh Kumar; Devi Prasad Sahu


Publisher
John Wiley and Sons
Year
2009
Weight
29 KB
Volume
40
Category
Article
ISSN
0931-7597

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Friedel-Crafts heteroarylation of (heter
✍ Shailesh Kumar; Devi Prasad Sahu 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 181 KB

## Abstract magnified image Anhydrous AlCl~3~‐mediated heteroarylation of various arenes and heteroarenes with 2,4‐dichloro‐quinazoline (**1**) and 4‐chloroquinoline (**4**) afforded exclusively 4‐aryl/heteroarylquinazolines (**3**) and 4‐aryl/heteroarylquinolines (**5**), respectively. Compared w