ChemInform Abstract: Formation and Cycloaddition of Nonstabilized N-Unsubstituted Azomethine Ylides from (2-Azaallyl)stannanes and (2-Azaallyl)silanes.
โ Scribed by William H. Pearson; Roger B. Clark
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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The Generation and Cycloaddition of 2-Azaallyl Anions and Azomethine Ylides from a Common Precursor. A Novel Synthesis of Indolizidines and Other Heterocycles. -Inter-or intramolecular N-alkylation of (azaallyl)stannanes or -silanes generates nonstabilized azomethine analogues which undergo cycloa
3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides. Part 7. Stereoselective Synthesis of Epibatidine and Analogues. -The key step in the synthesis of epibatidine (VII) and analogues like (VIII) and (XII) is the stereoselective [3 + 2] cycloaddition of the azomethine ylides (III) and (X). -(