ChemInform Abstract: A Formal Synthesis
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J. COSSY; M. CASES; D. GOMEZ PARDO
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Article
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2010
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John Wiley and Sons
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A Formal Synthesis of (-)-ฮฑ-Kainic Acid. -Starting from Lpyroglutamic acid (-)-(I), the known precursor (-)-(XVI) for the synthesis of the title compound is presented. The key step in this approach is the SmI 2 -mediated ketyl radical cyclization of the enecarbamate (X). Under irradiation condition