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ChemInform Abstract: First Total Synthesis of New Phenylpropanoid Lignans, (.+-.)-Aglacin K Stereoisomer and (.+-.)-Arborone.

✍ Scribed by Masaki Takahashi; Koji Takada; Daisuke Matsuura; Kunihiko Takabe; Hidemi Yoda


Publisher
John Wiley and Sons
Year
2008
Weight
28 KB
Volume
39
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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New Total Synthesis of (-)-and (+)-Chuangxinmycins. -Natural chuangxinmycin (VIII), which is effective in the treatment of E. coli caused infections, and its enantiomers are prepared starting from (+)-(I) or (+)-(II), respectively. Key steps in the synthesis of ( VIII) are the double enzymatic reso