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ChemInform Abstract: First Intramolecular Geminal Acylation: Synthesis of Bridged Bicyclic Diketones.

✍ Scribed by Angela N. Blanchard; D. Jean Burnell


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of the Fi
✍ J. D. BUYNAK; A. S. RAO; G. ADAM; S. D. NIDAMARTHY; H. ZHANG πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

Synthesis of the First 2',6 Bridged Penams. -The desired title compound (XII) is prepared from either the benzhydryl or the benzyl esters of 6-aminopenicillanic acid. This secondary tricyclic amine can be further functionalized to give tertiary amines, corresponding sulfones, and carboxylate salts.