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ChemInform Abstract: Facile Syntheses of Tris(trifluoromethyl)phosphine and Difluorotris( trifluoromethyl)phosphorane.

✍ Scribed by M. GOERG; G.-V. ROESCHENTHALER; A. A. KOLOMEITSEV


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: New Efficient Synth
✍ S. N. OSIPOV; A. S. GOLUBEV; N. SEWALD; K. BURGER πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 1 views

New Efficient Syntheses of Ξ±-Difluoromethyl-and Ξ±-Trifluoromethylornithine. -Ornithines (V), possessing a broad spectrum of biological activities including anticancer activity, are prepared in three steps. The key step is the regioselective alkylation of the imine (I) with the acetylide (II) in exc