Formation of α-Amino-Acid Amides and α-Hydroxy-Acid Amides by Degradation of Sugars with Primary Amines. -The title model reactions of glucose and ribose with an excess of propylamine represent a new mechanism for cross-linking of proteins through lysine side chains by sugars.
ChemInform Abstract: Facile Hydrolysis and Formation of Amide Bonds by N-Hydroxyethylation of α-Amino Acids.
✍ Scribed by J. W. SUGGS; R. M. PIRES
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract The hydrolysis reactions of __N__‐(__O__,__O′__‐diisopropyl)phosphoryl‐__L__‐__α__‐alanine (DIPP‐__L__‐__α__‐Ala), __N__‐(__O__,__O′__‐diisopropyl)‐ phosphoryl‐__D__‐__α__‐alanine (DIPP‐__D__‐__α__‐Ala), __N__‐(__O__,__O′__‐diisopropyl)phosphoryl‐__β__‐alanine (DIPP‐__β__‐Ala) and __N__