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ChemInform Abstract: Expeditious Synthesis of Enantiomerically Pure trans-4,5-Dihydroxy-2- cyclopenten-1-one.

โœ Scribed by K. TOYAMA; S. IGUCHI; T. OISHI; M. HIRAMA


Book ID
112030523
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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Addition of molecular fluorine to cis-2-cyclopentene-1 ,Cdiol gave the c&anti adduct stereoselectively. This meso diol was dissymmetrized by means of acetylation under lipase catalysis to afford the monoacetate with a high enatiomeric purity. Oxidation of the monoacetate followed by elimination of h