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ChemInform Abstract: Expedient Synthesis of 3-Hydroxyisoquinolines and 2-Hydroxy-1,4-naphthoquinones via One-Pot Aryne Acyl-Alkylation/Condensation.

โœ Scribed by Kevin M. Allan; Boram D. Hong; Brian M. Stoltz

Publisher
John Wiley and Sons
Year
2010
Weight
57 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A New Method to Pre
ChemInform Abstract: A New Method to Prepare 3-Alkyl-2-hydroxy-1,4-naphthoquinones: Synthesis of Lapachol and Phthiocol.
โœ Sabrina Baptista Ferreira; David Rodrigues da Roche; Jose Walkimar M. Carneiro; ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons โš– 24 KB

## Abstract Lawsone (I) is used as starting material for the optimized reductive alkylation process to yield the title compounds including phthiocol (IIa) and lapachol (IIIb).