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ChemInform Abstract: Enzymatic Synthesis of 3-Deoxy-D-manno-octulosonate 8-Phosphate, 3-Deoxy-D-altro-octulosonate 8-Phosphate, 3,5-Dideoxy-D-gluco(manno)-octulosonate 8-Phosphate by 3-Deoxy-D-arabino-heptulosonate 7-Phosphate Synthase.

โœ Scribed by Galina Ya. Sheflyan; David L. Howe; Trudy L. Wilson; Ronald W. Woodard

Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
30
Category
Article
ISSN
0931-7597

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3-Deoxy-D-manm-octulosonate-8-phosphate (KDOP) synthase catalyzes the production of KDOP from phosphoenolpyruvate (PEP) and arabinose-5-phosphate (A5P). In gram-negative bacteria KDOP is subsequently dephosphorylated, cytidylylated, and linked to lipid A and is required for lipid A incorporation int