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ChemInform Abstract: Enzymatic Peptide Synthesis with p-Guanidinophenyl and p-(Guanidinomethyl)phenyl Esters as Acyl Donors.

✍ Scribed by H. SEKIZAKI; K. ITOH; E. TOYOTA; K. TANIZAWA

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Enzymatic Peptide Synthesis with p-Guanidinophenyl and p-(Guanidinomethyl)phenyl Esters as Acyl Donors.

-Two series of "inverse substrates", e.g. (VII) and (IV), are prepared as acyl donor components for enzymatic peptide synthesis. These substrates are found to couple readily with amino acid p-nitroanilides as acyl acceptors to produce peptides.

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