ChemInform Abstract: Entry to the 2,5-Epoxyimidazo[1,5-a][1,3]diazocine and 5,8-Epoxy[1,2,3]triazolo[1,5-a][1,3]diazocine Systems: Novel Reversed Cyclonucleoside Analogues.

✍ Scribed by D. F. Ewing; G. Goethals; G. Mackenzie; P. Martin; G. Ronco; L. Vanbaelinghem; P. Villa

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199939191

✦ Synopsis

Entry to the 2,5-Epoxyimidazo [1,5-a][1,3]diazocine and 5,8-Epoxy[1,2,3]triazolo [1,5-a][1,3]diazocine Systems:

Novel Reversed Cyclonucleoside Analogues.

-Upon deprotection the two compounds (III) and (VIII) cyclize spontaneously and regiospecifically to form the novel reversed cyclonucleosides (IV) and (IX), respectively. The shape of (IX) is studied by molecular modelling.

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