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ChemInform Abstract: Enantioselective Total Synthesis and Structure Determination of the Mercapturic Acid Sulfoxide Conjugate.

✍ Scribed by S. NAKAMURA; K. GOTO; M. KONDO; S. NAITO; Y. TSUDA; K. SHISHIDO


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Enantioselective Total Synthesis and Structure Determination of the Mercapturic Acid Sulfoxide Conjugate.

-Key step in the synthesis of the mercapturic acid sulfoxide (IV), a metabolite of anti-inflammatory drug DUP 697, is the diastereoselective oxidation of the sulfide (II) to the sulfoxide (III). -(


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