ChemInform Abstract: Enantioselective Synthesis of lyxo-(2R,3R,4R)-C18-Phytosphingosine Using Double Stereodifferentiation.
β Scribed by Catherine Martin; William Pruenck; Michel Bortolussi; Robert Bloch
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
The first diastereoselective synthesis of L-xylo -(2R,3S,4S)-C 18 -phytosphingosine (1) has been achieved by double stereodifferentiation of enantiomerically enriched terminal olefin 14 using (DHQD) 2 -PHAL ligand in an asymmetric dihydroxylation with a diastereomeric ratio of 83:17. This phytosphin