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ChemInform Abstract: Enantioselective Synthesis of lyxo-(2R,3R,4R)-C18-Phytosphingosine Using Double Stereodifferentiation.

✍ Scribed by Catherine Martin; William Pruenck; Michel Bortolussi; Robert Bloch


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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πŸ“œ SIMILAR VOLUMES


Double stereodifferentiation in asymmetr
✍ Rodney A Fernandes; Pradeep Kumar πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 76 KB

The first diastereoselective synthesis of L-xylo -(2R,3S,4S)-C 18 -phytosphingosine (1) has been achieved by double stereodifferentiation of enantiomerically enriched terminal olefin 14 using (DHQD) 2 -PHAL ligand in an asymmetric dihydroxylation with a diastereomeric ratio of 83:17. This phytosphin