A case study concerning the development of enantioselective hydrogenation processes for aliphatic a-ketoesters, particularly ethyl 2-oxo-4-phenylbutyrate (1) and ethyl pyruvate (2), using homogeneous Rh-diphosphine and heterogeneous Pt/A1203cinchona catalysts is presented. Important parameters to ob
ChemInform Abstract: Enantioselective Hydrogenation of α-Keto Esters: Comparison of Homogeneous and Heterogeneous Catalysts
✍ Scribed by H.-U. BLASER; H.-P. JALETT; F. SPINDLER
- Book ID
- 112039636
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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1999 stereochemistry stereochemistry (general, optical resolution) O 0030 ## 48 -029 Enantioselective Hydrogenation of α-Keto Acetals with Cinchona Modified Pt Catalyst. -The title reaction is investigated in more detail also concerning the modifier and the reaction conditions such as catalyst, so