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ChemInform Abstract: Enantioselective Friedel—Crafts Alkylation of Indoles with Aromatic α,β-Unsaturated Aldehydes Catalyzed by Diphenylprolinol Silyl Ether.

✍ Scribed by Zhi-Jing Wang; Jian-Guo Yang; Jun Jin; Xin Lv; Weiliang Bao

Publisher: John Wiley and Sons
Year: 2010
Weight: 35 KB
Volume: 41
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201016095

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## Abstract magnified image The Lewis base‐Lewis base bifunctional catalytic system has been developed and successfully applied to the asymmetric Friedel–Crafts alkylation of indoles with α,β‐unsaturated aldehydes. The reactions are promoted by chiral diphenylprolinol trimethylsilyl ether in the p