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ChemInform Abstract: CaSH Organocatalysis: Enantioselective Friedel—Crafts Alkylation of Indoles with α,β-Unsaturated Aldehydes.

✍ Scribed by Tian Tian; Bao-Jian Pei; Qing-Hua Li; Hao He; Ling-Yan Chen; Xiang Zhou; Wing-Hong Chan; Albert W. M. Lee

Publisher
John Wiley and Sons
Year
2009
Weight
30 KB
Volume
40
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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An Efficient Enantioselective Method for
An Efficient Enantioselective Method for Asymmetric Friedel–Crafts Alkylation of Indoles with α,β-Unsaturated Aldehydes
✍ Liang Hong; Lei Wang; Chao Chen; Bangzhi Zhang; Rui Wang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 190 KB 👁 2 views

## Abstract magnified image The Lewis base‐Lewis base bifunctional catalytic system has been developed and successfully applied to the asymmetric Friedel–Crafts alkylation of indoles with α,β‐unsaturated aldehydes. The reactions are promoted by chiral diphenylprolinol trimethylsilyl ether in the p