ChemInform Abstract: Efficient Synthesis of a Novel Estrone—Talaromycin Hybrid Natural Product.
✍ Scribed by L. TIETZE; G. SCHNEIDER; J. WOELFLING; T. NOEBEL; C. WULFF; I. SCHUBERT; A. RUEBELING
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Hetero-Diels-Alder reaction of the steroidal exocyclic enol ethers 14 and 15, obtained from the secoestrones 8 and 9 by reduction, iodoetherification, and elimination, with ethyl O-benzoyldiformylacetate (16) leads to the spiroacetals 17 and 18 as a mixture of four diastereomers. Reduction of the ma
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