A Novel Approach in Drug Discovery: Synt
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Lutz F. Tietze; Gyula Schneider; János Wölfling; Anja Fecher; Thomas Nöbel; Sönk
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Article
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2000
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John Wiley and Sons
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English
⚖ 132 KB
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Hetero-Diels-Alder reaction of the steroidal exocyclic enol ethers 14 and 15, obtained from the secoestrones 8 and 9 by reduction, iodoetherification, and elimination, with ethyl O-benzoyldiformylacetate (16) leads to the spiroacetals 17 and 18 as a mixture of four diastereomers. Reduction of the ma