ChemInform Abstract: Efficient Palladium-Catalyzed Synthesis of Aminopyridyl Phosphonates from Bromopyridines and Diethyl Phosphite.
β Scribed by Alla Bessmertnykh; Christiane Morkos Douaihy; Sankar Muniappan; Roger Guilard
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 36 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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An Efficient Synthesis of Tetraethyl Fluoromethylenediphosphonate and Derivatives from Diethyl Dibromofluoromethylphosphonate. -Treatment of phosphonate (I) with an equivalent amount of BuLi and subsequent quenching with a variety of electrophiles provides an efficient synthesis of pharmaceutically