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ChemInform Abstract: Efficient Generation of Trifluoroacetaldehyde and Successive Reaction with Imines Affording β-Hydroxy-β-trifluoromethyl Ketones.

✍ Scribed by Kazumasa Funabiki; Kei Matsunaga; Masaki Matsui; Katsuyoshi Shibata


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Reaction of Monocar
✍ M. OCHIAI; Y. KITAGAWA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Reaction of Monocarbonyl Iodonium Ylides with Activated Imines: Stereoselective Synthesis of trans-and cis-α,β-Aziridino Ketones. -Treatment of iodonium salts (I) with lithium ethoxylate generates monocarbonyl iodonium ylides which readily undergo alkylidene-transfer reactions with activated imines.