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ChemInform Abstract: Dual IGF-1R/SRC Inhibitors Based on a N′-Aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide Structure.

✍ Scribed by Stefanie Schmidt; Lutz Preu; Thomas Lemcke; Frank Totzke; Christoph Schaechtele; Michael H. G. Kubbutat; Conrad Kunick

Book ID: 102070797
Publisher: John Wiley and Sons
Year: 2011
Weight: 39 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201141098

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ChemInform Abstract: Structure—Activity Relationship for a Series of 2-Substituted 1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indoles: Potent Subtype-Selective Inhibitors of N-Methyl-D-aspartate (NMDA) Receptors.

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Structure-Activity Relationship for a Series of 2-Substituted 1,2,3,4-Tetrahydro-9H-pyrido [3,4-b]indoles: Potent Subtype-Selective Inhibitors of N-Methyl-D-aspartate (NMDA) Receptors. -In continuation of an earlier work a series of pyridoindole-based compounds such as (III) and (VI) are synthesize