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ChemInform Abstract: Domino Michael Aldol and Domino Michael Mannich Reactions: Highly Stereoselective Synthesis of Functionalized Cyclohexanes.

✍ Scribed by Christoph Schneider; Oliver Reese

Publisher: John Wiley and Sons
Year: 2000
Weight: 31 KB
Volume: 31
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200048095

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Abstract

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## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c