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ChemInform Abstract: Direct-Type Aldol Reactions of Fluorenylidene-Protected/Activated Glycine Esters with Aldehydes for the Synthesis of β-Hydroxy-α-amino Acid Derivatives.

✍ Scribed by Raphael Rahmani; Masatoshi Matsumoto; Yasuhiro Yamashita; Shu Kobayashi


Book ID
115552684
Publisher
John Wiley and Sons
Year
2012
Weight
32 KB
Volume
43
Category
Article
ISSN
0931-7597

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## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di