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ChemInform Abstract: Direct Synthesis of Fmoc-Protected Amino Acids Using Organozinc Chemistry: Application to Polymethoxylated Phenylalanines and 4-Oxoamino Acids.

โœ Scribed by Herve J. C. Deboves; Christian A. G. N. Montalbetti; Richard F. W. Jackson


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
32
Category
Article
ISSN
0931-7597

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A New Approach to the Synthesis of Di-and Tripeptides with Unnatural Amino Acids Using Organozinc Chemistry. -Di-and tripeptides which incorporate an iodoalanine unit can be converted into the corresponding organozinc reagents, which react with electrophiles either under palladium catalysis, or by