ChemInform Abstract: Direct, One-Pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents Through Lactam/Amide Activation.

✍ Scribed by Kai-Jiong Xiao; Jie-Min Luo; Ke-Yin Ye; Yu Wang; Pei-Qiang Huang

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 68 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201032065

✦ Synopsis

Abstract

The title reaction provides a highly efficient and general method to prepare cyclic and acyclic tertiary amines.