ChemInform Abstract: Diels—Alder Reactions of Ethyl α-Bromoacrylate with Open-Chain Dienes — Synthesis of Ethyl 1,3-/1,4-Cyclohexadienecarboxylates.
✍ Scribed by Yingjie Li; Quanrui Wang; Goeke Andreas
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The title reaction proceeds with high regio‐ and diastereoselectivity.
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Reaction of Ethyl 4,4,4-Trifluoroacetoacetate Enolate with 3-Bromo-1,1, 1-trifluoroacetone: Synthesis of 2,4-Bis(trifluoromethyl)furan. -The title reaction follows competing courses such as C-acylation, O-alkylation and di-O-alkylation which result in the formation of two major products (III) and (I