ChemInform Abstract: Diastereoselective Synthesis of β-Amino Alcohols via Bu3SnH-Mediated Reductive Cyclization of Carbonyl—Oxime Ethers.
✍ Scribed by J. TORMO; D. S. HAYS; G. C. FU
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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A Concise Synthesis of Rigidified β-Amino Acids via Sulfanyl Radical Addition-Cyclization of Oxime Ethers and Hydrazones. -Sulfanyl radical cyclization of alkenyl-tethered oxime ethers and hydrazones (I) provides cis/trans mixtures of the cyclized products (III) and (IV). The cyclopentylamines (III
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