Anomeric Ξ±and Ξ²-N,O-psiconucleosides were prepared by 1,3-dipolar cycloaddition of C-ethoxycarbonyl N-methyl nitrone with ethyl 2-acetyloxyacrylate, followed by VorbrΓΌggen nucleosidation. The synthetic scheme has been applied to all purine and pyrimidine nucleobases. Nucleosidation can proceed under
β¦ LIBER β¦
ChemInform Abstract: Diastereoselective Synthesis of N,O-Psiconucleosides, a New Class of Modified Nucleosides.
β Scribed by Ugo Chiacchio; Antonino Corsaro; Venerando Pistara; Antonio Rescifina; Daniela Iannazzo; Anna Piperno; Giovanni Romeo; Roberto Romeo; Giovanni Grassi
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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