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ChemInform Abstract: Diastereoselective Synthesis of Enantiomerically Pure 1,2-Disubstituted Cyclopropanols from Allylic Sulfones.

✍ Scribed by D. Diez; P. Garcia; M. P. Pacheco; I. S. Marcos; N. M. Garrido; P. Basabe; J. G. Urones


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Synthesis of Enantiomerically Pure Vinylcyclopropanes by S N 2' Allylic Carboxylate Displacements. -The readily available optically pure lactones (I) or (XIII) undergo palladium-catalyzed displacement by a variety of stabilized carbon, oxygen, and nitrogen nucleophiles to afford as major S N 2' prod