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ChemInform Abstract: Diastereoselective Synthesis of an Isoprostane: (.+-.)-8-epi-PFG2. alpha. Ethyl Ester.

โœ Scribed by D. F. TABER; R. J. HERR; D. M. GLEAVE


Book ID
112042413
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Total Synthesis of
โœ A. GUY; T. DURAND; J.-P. VIDAL; J.-C. ROSSI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

Total Synthesis of 15(RS)-5,6-Dehydro-8-epi-PGF2ฮฑ Methyl Ester by a Biomimetic Process. -Using diacetone D-glucose (I) as starting material the first total synthesis of the title compound (IV) is achieved. Key step is a final biomimetic 5-exo-radical cyclization of the highly functionalized precurs