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ChemInform Abstract: An Efficient One-Pot Synthesis of Hippuric Acid Ethyl Ester Derivatives.

✍ Scribed by S. C. CONWAY; R. B. PERNI


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
29
Category
Article
ISSN
0931-7597

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Efficient one-pot synthesis of N-ethyl a
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Mono-N-ethylated h-amino acid esters are obtained in high yields using reductive amination procedures. Formation of imine is achieved by excess of acetaldehyde, followed by removal of acetaldehyde and reduction by NaBH(OAc) 3 . The elaborated one-pot synthesis allows for the efficient synthesis of s