ChemInform Abstract: Diastereoselective Access to trans-2-Substituted Cyclopentylamines.
β Scribed by Antoine Joosten; Emilie Lambert; Jean-Luc Vasse; Jan Szymoniak
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 26 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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Stereoselective Access to Substituted Enediyne Building Blocks. -Coupling/elimination of disubstituted propargyl bromides in the presence of LiN(Tms) 2 results in formation of tetrasubstituted olefins. The E:Z selectivity strongly depends on the nature of the propargylic substituent R. -(HYND,