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ChemInform Abstract: Determination of the Absolute Configuration of α-Amino-2- alkylthiazoles by Circular Dichroism.

✍ Scribed by F. L. MERCHAN; P. MERINO; I. ROJO; T. TEJERO; A. DONDONI


Book ID
112027183
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
27
Category
Article
ISSN
0931-7597

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The absolute configuration of the (À)-enantiomer of mirtazapine was determined by means of vibrational circular dichroism (VCD). The observed VCD of (À)-mirtazapine showed excellent correlation with the calculated VCD of the (R)-enantiomer. This is in agreement with the absolute configuration as det