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ChemInform Abstract: Design, Synthesis and Evaluation of a Novel Series of Spiroketals Based on the Structure of the Antibacterial Gyrase Inhibitor Novobiocin.

✍ Scribed by W. BELL; M. H. BLOCK; C. COOK; J A. GRANT; D. TIMMS


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design, Synthesis,
✍ F. MASSIERE; M.-A. BADET-DENISOT; L. RENE; B. BADET πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 27 KB πŸ‘ 2 views

Design, Synthesis, and Evaluation of the First Mechanism-Based Inhibitor of Glucosamine 6-Phosphate Synthase. -The first example of the title inhibitor, the compound (I), a glutamine derivative bearing a latent electrophilic function, is prepared starting from suitably protected glutamine. (I) is st