ChemInform Abstract: Discovery of 1,6-Na
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Laval Chan; Haolun Jin; Tomislav Stefanac; Jean-Francois Lavallee; Guy Falardeau
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Article
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2010
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John Wiley and Sons
β 32 KB
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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors. -A series of 20 1,6-naphthyridines, e.g. (I), is synthesized by amidation of key intermediate (IV) and in case of its halogen analogue (V) by subsequent Stille coupling with stannanes, e.g. (V