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ChemInform Abstract: Design, Synthesis and Bioactivity of Novel ALS Inhibitors. Part 7. The Synthesis of Novel Acetolactate Synthase Inhibitors, N-(Asymmetrically Disubstituted Phosphoryl)-N′-(4,6-dimethoxypyrimidin-2-yl) Ureas.

✍ Scribed by Guo-Feng Zhao; Hua-Zheng Yang; Yong-Hong Li

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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The synthesis of novel acetolactate synt
The synthesis of novel acetolactate synthase inhibitors, N-(asymmetrically disubstituted phosphoryl)-N′-(4,6-dimethoxypyrimidin-2-yl) ureas
✍ Guo-Feng Zhao; Hua-Zheng Yang; Yong-Hong Li 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB 👁 2 views

In view of the isosterism of the sulfonyl group(-SO 2 -) and the phosphoryl group, two new types of compounds N-(N-aryl-O-alkyl phosphoryl)-NЈ-(4,6dimethoxypyrimidin-2-yl) ureas (2) and N-(N-aryl-Nalkylphosphoryl) -NЈ -(4, 6 -dimethoxypyrimidin -2-yl) ureas (3) were designed and synthesized by treat