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ChemInform Abstract: Design, Synthesis and Antiproliferative Activities of Biarylolefins Based on Polyhydroxylated and Carbohydrate Scaffolds.

✍ Scribed by Alexandre Novoa; Nadia Pellegrini-Moise; Stephane Bourg; Sylviane Thoret; Joelle Dubois; Genevieve Aubert; Thierry Cresteil; Yves Chapleur


Publisher
John Wiley and Sons
Year
2011
Weight
43 KB
Volume
43
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design, Synthesis,
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Design, Synthesis, and Biological Evaluation of Carbohydrate-Based Mimetics of cRGDFV. -Carbohydrate-based non-peptide mimetics such as (I), (II), and (III) of the potent cyclopeptide title antagonist of Ξ±vΞ²3 and . alpha.vΞ²5 integrins are synthesized and evaluated in cell adhesion assays. Only the c