Design, Construction and Properties of Peptide N-Terminal Cap Templates Devised to Initiate α-Helices. Part 2. Caps Derived from N-[(2S)-2-Chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-thioPro-OMe.
✦ LIBER ✦
ChemInform Abstract: Design, Construction and Properties of Peptide N-Terminal Cap Templates Devised to Initiate α-Helices. Part 1. Caps Derived from N-(4-Chlorobutyryl)-(2S)-Pro-(2S)-Pro-(2S)-Ala-OMe and N-[(2S)-2-Chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-hydroxyPro-OMe.
✍ Scribed by Arwel Lewis; Martin D. Ryan; David Gani
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Design, Construction and Properties of Peptide N-Terminal Cap Templates Devised to Initiate α-Helices. Part 1. Caps Derived from N-(4-Chlorobutyryl)-(2S)-Pro-(2S)-Pro-(2S)-Ala-OMe and N-[(2S)-2-Chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-hydroxyPro-OMe.
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Design, Synthesis, Structure and Properties of an α-Helix Cap Template Derived from N-[(2S)-2-Chloropropionyl]-(2S)-Pro-(2R)-Ala-(2S,4S)-4-thioPro-OMe which Initiates α-Helical Structures. -Each amide bond of the 12-membered macrocyclic template, derived from the title peptide, exists in the trans-r