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ChemInform Abstract: Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen.

✍ Scribed by R. M. ADLINGTON; J. E. BALDWIN; B. CHEN; S. L. COOPER; W. MCCOULL; G. J. PRITCHARD; T. J. HOWE; G. W. BECKER; R. B. HERMANN; A. M. MCNULTY; B. L. NEUBAUER

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design and Synthesi
ChemInform Abstract: Design and Synthesis of Monocyclic β-Lactams as Mechanism-Based Inhibitors of Human Cytomegalovirus Protease.
✍ A. D. BORTHWICK; G. WEINGARTEN; T. M. HALEY; M. TOMASZEWSKI; W. WANG; Z. HU; J. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Design and Synthesis of Monocyclic β-Lactams as Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. -Starting from monocyclic β-lactams novel human cytomegalovirus protease inhibitors, e.g. (III), (VII),and (VIII), are developed. The most potent one among them is the derivative (VII) with