ChemInform Abstract: Design and Synthesis of New Chiral Pyridine—Phosphite Ligands for the Copper-Catalyzed Enantioselective Conjugate Addition of Diethylzinc to Acyclic Enones.
✍ Scribed by Yinjun Xie; Hanmin Huang; Weimin Mo; Xiangqun Fan; Zhiqiang Shen; Zhenlu Shen; Nan Sun; Baoxiang Hu; Xinquan Hu
- Publisher
- John Wiley and Sons
- Year
- 2009
- Weight
- 38 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract New amino acid‐based modular chiral ligands were readily synthesized and used to catalyze the asymmetric conjugate addition of Et~2~Zn to various cyclic enones in the presence of a variety of copper sources. Moderately high __ee__ of up to 72% were obtained using ligand (__S__)‐**1e** u