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ChemInform Abstract: Design and Synthesis of Estrarubicin: A Novel Class of Estrogen-Anthracenedione Hybrids.

✍ Scribed by F. DE RICCARDIS; D. MEO; I. IZZO; M. DI FILIPPO; A. CASAPULLO

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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Design and Synthesis of Estrarubicin: a
Design and Synthesis of Estrarubicin: a Novel Class of Estrogen-Anthracenedione Hybrids
✍ Francesco De Riccardis; Daniela Meo; Irene Izzo; Marcello Di Filippo; Agostino C πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 369 KB πŸ‘ 2 views

The synthesis of estrarubicin, a member of a new class of LiClO 4 in diethyl ether, revealed notable diastereofacial selectivity of the diene, leading mainly to cycloadduct 8. estrogen-anthraquinone hybrids, has been accomplished in an 8-step sequence starting from estrone. The octacyclic Elaboratio